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Pomaglumetad Methionil

Chemical Structure : Pomaglumetad Methionil

CAS No.: 635318-55-7

Pomaglumetad Methionil (LY2140023 monohydrate)

Catalog No.: PC-61613Not For Human Use, Lab Use Only.

Pomaglumetad Methionil (LY2140023 monohydrate) is the methionine amide prodrug of the mGluR2/3 agonist LY-404039 with the potential oral treatment of schizophrenia..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Pomaglumetad Methionil (LY2140023 monohydrate) is the methionine amide prodrug of the mGluR2/3 agonist LY-404039 with the potential oral treatment of schizophrenia.

Schizophrenia

Phase 1 Clinical

Physicochemical Properties

M.Wt 366.403
Formula C12H18N2O7S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,4S,5S,6S)-4-((S)-2-amino-4-(methylthio)butanamido)-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide hydrate

References

1. Patil ST, et al. Nat Med. 2007 Sep;13(9):1102-7.

2. Fell MJ, et al. J Pharmacol Exp Ther. 2008 Jul;326(1):209-17.

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