Chemical Structure : Purfalcamine
CAS No.:
1038620-68-6
Purfalcamine
Catalog No. : PC-62162Not For Human Use, Lab Use Only.
Purfalcamine is a potent, specific inhibitor of Plaasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) with IC50 of 17 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6216201
Biological Activity
Purfalcamine is a potent, specific inhibitor of Plaasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1 ) with IC50 of 17 nM.
Physicochemical Properties
M.Wt
528.636
Formula
C29H33FN8O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
[4-[[2-[(4-aminocyclohexyl)amino]-9-(3-fluorophenyl)purin-6-yl]amino]phenyl]-piperidin-1-ylmethanone
References
1. Kato N, et al. Nat Chem Biol.
2. Bansal A, et al. J Biol Chem.
3. Gaji RY, et al. Antimicrob Agents Chemother.
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