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Chemical Structure : Pyrimethamine
CAS No.: 58-14-0
Catalog No.: PC-45409Not For Human Use, Lab Use Only.
Pyrimethamine is a synthetic derivative of ethyl-pyrimidine with potent antimalarial properties, interferes with the regeneration of tetrahydrofolic acid from dihydrofolate by competitively inhibiting DHFR, has also been found to reduce the expression of SOD1.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $128 | In stock | |
| 500 mg | $298 | In stock | |
| 1 g | $398 | In stock | |
| 5 g | Get quote |
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Pyrimethamine is a synthetic derivative of ethyl-pyrimidine with potent antimalarial properties, interferes with the regeneration of tetrahydrofolic acid from dihydrofolate by competitively inhibiting DHFR, has also been found to reduce the expression of SOD1.
| M.Wt | 248.7114 | |
| Formula | C12H13ClN4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2,4-Pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl- |
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1. Lange DJ, et al. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Apr;14(3):199-204.
2. Wright PD, et al. Neurosci Lett. 2010 Oct 4;482(3):188-92.
3. Martins-Duarte ÉS, et al. Exp Parasitol. 2013 Mar;133(3):294-9.
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