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Q151

Chemical Structure : Q151

CAS No.: 2226449-95-0

Q151 (Q 151;Q151)

Catalog No.: PC-35157Not For Human Use, Lab Use Only.

Q151 is a highly potent inhibitor of mycobacterium tuberculosis IMPDH2 (MtbIMPDH2) with Kiapp of 18 nM, demonstrates the minimum inhibitory concentrations (MIC) of 1 uM withour significant cytotoxicity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Q151 is a highly potent inhibitor of mycobacterium tuberculosis IMPDH2 (MtbIMPDH2) with Kiapp of 18 nM, demonstrates the minimum inhibitory concentrations (MIC) of 1 uM withour significant cytotoxicity.

    Physicochemical Properties

    M.Wt 418.404
    Formula C23H16F2N4O2
    CAS No. 2226449-95-0
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name

    (S)-N-(2-(4-Cyanophenyl)benzo[d]oxazol-5-yl)-2-((2,3-difluorophenyl)amino)propanamide

    References

    1. Chacko S, et al. J Med Chem. 2018 May 30. doi: 10.1021/acs.jmedchem.7b01839.

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