Q151 | Mtb IMPDH2 inhibitor | Probechem Biochemicals

Chemical Structure : Q151

Q151 (Mtb IMPDH2 inhibitor, Q-151)

Catalog No.: PC-35157Not For Human Use, Lab Use Only.

Q151 is a highly potent inhibitor of mycobacterium tuberculosis IMPDH2 (Mtb IMPDH2) with Kiapp of 18 nM, demonstrates the minimum inhibitory concentrations (MIC) of 1 uM withour significant cytotoxicity.

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Biological Activity

Q151 is a highly potent inhibitor of mycobacterium tuberculosis IMPDH2 (Mtb IMPDH2) with Kiapp of 18 nM, demonstrates the minimum inhibitory concentrations (MIC) of 1 uM withour significant cytotoxicity.

Physicochemical Properties

M.Wt	418.404
Formula	C23H16F2N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(2-(4-Cyanophenyl)benzo[d]oxazol-5-yl)-2-((2,3-difluorophenyl)amino)propanamide

References

1. Chacko S, et al. J Med Chem. 2018 May 30. doi: 10.1021/acs.jmedchem.7b01839.

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Q151 (Mtb IMPDH2 inhibitor, Q-151)

Biological Activity

Physicochemical Properties

References

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