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Chemical Structure : Quin-C1
Catalog No.: PC-20393Not For Human Use, Lab Use Only.
Quin C1 is a potent and selective FPR2 agonist with EC50 of 15 nM, induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells.
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Quin C1 is a potent and selective FPR2 agonist with EC50 of 15 nM, induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells.
Quin C1 induces neutrophil chemotaxis and degranulation in vitro.
Quin C1 reduces neutrophil and lymphocyte counts in bronchoalveolar lavage fluid in a mouse lung injury model.
Quin C1 exhibits anti-inflammatory property in a mouse model of bleomycin-induced lung injury.
| M.Wt | 445.52 | |
| Formula | C26H27N3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nanamori M et al. Mol. Pharmacol, 2004, 66, 1213–1222.
2. Min He, et al. Acta Pharmacol Sin. 2011 May;32(5):601-10.
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