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Chemical Structure : Quinalizarin
Catalog No.: PC-62192Not For Human Use, Lab Use Only.
Quinalizarin is a potent, selective and cell-permeable inhibitor of CK2 with Ki of 58 nM.
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Quinalizarin is a potent, selective and cell-permeable inhibitor of CK2 with Ki of 58 nM.
Quinalizarin shows selectivity over DYRK1a, PIMs, HIPK2, MNK1, ERK8 and PKD1.
Quinalizarin inhibits endogenous CK2 and induces apoptosis more efficiently than Emodin in Jurkat cells.
Quinalizarin reduces cell viability with emphasis on adenocarcinoma cells harboring EGFR sensitive mutation, suppresses migration, and accelerates apoptosis in different human lung cancer cell lines.
| M.Wt | 272.212 | |
| Formula | C14H8O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Cozza G, et al. Biochem J. 2009 Jul 15;421(3):387-95.
2. Zhou Y, et al. Indian J Cancer. 2015 Dec;52 Suppl 2:e119-24.
3. Pan X, et al. Int J Oncol. 2016 Mar;48(3):1073-84.
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