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Chemical Structure : RAMX3
Catalog No.: PC-61172Not For Human Use, Lab Use Only.
RAMX3 is a tritium-labeled allosteric modulator of the human chemokine receptor CXCR3 with Kd of 1.08 nM.
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RAMX3 is a tritium-labeled allosteric modulator of the human chemokine receptor CXCR3 with Kd of 1.08 nM.
In radioligand displacement assays shows potent negative cooperativity between RAMX3 and chemokine CXCL11, providing a basis for the use of RAMX3 to investigate other potential allosteric modulators.
| M.Wt | 631.693 | |
| Formula | C33H32T3F4N5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bernat V, et al. ACS Chem Biol. 2014 Nov 21;9(11):2664-77.
2. Bernat V, et al. ChemMedChem. 2012 Aug;7(8):1481-9.
3. Milanos L, et al. Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15277-15281.
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