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Chemical Structure : RC-752
Catalog No.: PC-21055Not For Human Use, Lab Use Only.
RC-752 is a potent, seletive sigma-1 receptor (S1R) antagonist with Ki of 6.2 nM, 50-fold selective over S2R, shows antinociceptive activity.
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RC-752 is a potent, seletive sigma-1 receptor (S1R) antagonist with Ki of 6.2 nM, 50-fold selective over S2R, shows antinociceptive activity.
RC-752 shows no cytotoxic effect in two normal human cell lines or in an in vivo zebrafish model.
RC-752 effectively alleviated pain the formalin test and the spinal nerve ligation model of neuropathic pain (NP).
| M.Wt | 309.45 | |
| Formula | C21H27NO | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Giacomo Rossino, et al. Pharmaceuticals (Basel)
. 2023 Jul 5;16(7):962.
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