RIG-I agonist 95

Chemical Structure : RIG-I agonist 95

Catalog No.: PC-28668Not For Human Use, Lab Use Only.

RIG-I agonist 95 is a potent, direct-acting small-molecule RIG-I agonist, shows SPR KD of 9.5 uM for full-length RIG-I, activates the RIG-I pathway with high specificity and low cytotoxicity, selectively activates IFNs and ISGs in cellulo.

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Biological Activity

Physicochemical Properties

M.Wt	441.31
Formula	C23H18Cl2N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((3,4-dichlorophenyl)(phenyl)methyl)-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide

References

1. Guo R, et al. Nat Commun. 2026 Oct 19;17(1):10366.

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RIG-I agonist 95

Biological Activity

Physicochemical Properties

References

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