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RIPK2 inhibitor 3

Chemical Structure : RIPK2 inhibitor 3

CAS No.: 1579965-17-5

RIPK2 inhibitor 3

Catalog No.: PC-49810Not For Human Use, Lab Use Only.

RIPK2 inhibitor 3 is a potent, selective inhibitor of RIP2 kinase (RIPK2), displays equivalent potency to inhibitor RIPK2 inhibitor 3 in biochemical assays, phosphate ester prodrug.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    RIPK2 inhibitor 3 is a potent, selective inhibitor of RIP2 kinase (RIPK2), displays equivalent potency to inhibitor RIPK2 inhibitor 3 in biochemical assays, phosphate ester prodrug.
    RIPK2 inhibitor 3 has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human IBD explant samples.

    Physicochemical Properties

    M.Wt 631.64
    Formula C21H28CaN4O10PS2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Calcium(I) 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Hydrogen Phosphate Trihydrate

    References

    1. Pamela A Haile, et al. J Med Chem. 2019 Jul 25;62(14):6482-6494.

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