Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : RO-0335
CAS No.: 867365-76-2
Catalog No.: PC-49139Not For Human Use, Lab Use Only.
RO-0335 is a highly potent, selective nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with IC50 of 8.1 nM, potently inhibits HIV replication with IC50 of 1.3 nM in cell based assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $198 | In stock | |
| 25 mg | $348 | In stock | |
| 50 mg | $548 | In stock | |
| 100 mg | Get quote | ||
| 1 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
RO-0335 is a highly potent, selective nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with IC50 of 8.1 nM, potently inhibits HIV replication with IC50 of 1.3 nM in cell based assays.
RO-0335 shows potent inhibition of Wt HIV-1 with IC50 of 1.1 nM and retains activity (protein shifted IC50 < 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.
| M.Wt | 573.214 | |
| Formula | C21H13BrCl2FN3O4S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide |
|
1. H Javanbakht, et al. Antiviral Res. 2010 May;86(2):212-9.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
