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RO5454291

Chemical Structure : RO5454291

CAS No.: 2738687-98-2

RO5454291 (RO 5454291)

Catalog No.: PC-63452Not For Human Use, Lab Use Only.

RO5258638 is a small molecule inhibitor of CDK5-p25 protein-protein interaction with IC50 of 1.39 uM..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    RO5258638 is a small molecule inhibitor of CDK5-p25 protein-protein interaction with IC50 of 1.39 uM.

    Physicochemical Properties

    M.Wt 357.458
    Formula C19H27N5O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-(3-((6-methoxypyridin-2-yl)amino)-6,6-dimethyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl)-2,2-dimethylbutan-1-one

    References

    1. Bellón-Echeverría I, et al. Sci Rep. 2018 Mar 23;8(1):5083.

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