ROC-0929 (ROC0929)

Chemical Structure : ROC-0929

CAS No.: 1048660-43-0

Catalog No.: PC-26344Not For Human Use, Lab Use Only.

ROC-0929 is a specific small molecule inhibitor of secreted phospholipase A2 group X (sPLA2-X, sPLA2s) with IC50 of 80 nM (hGX sPLA2), does not inhibit other mammalian sPLA2s.

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Biological Activity

ROC-0929 is a specific small molecule inhibitor of secreted phospholipase A2 group X (sPLA2-X, sPLA2s) with IC50 of 80 nM (hGX sPLA2), does not inhibit other mammalian sPLA2s.

Physicochemical Properties

M.Wt	561.65
Formula	C30H31N3O6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-indol-4-yl)oxy)-N-(phenylsulfonyl)propanamide

References

1. Oslund RC, et al. J Med Chem. 2008;51:4708–4714.

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ROC-0929 (ROC0929)

Biological Activity

Physicochemical Properties

References

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