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Chemical Structure : RORγt-IN-9a
Catalog No.: PC-60488Not For Human Use, Lab Use Only.
A potent, selective, CNS penetrant, orally bioavailable RORγt with pIC50 of 8.3 in FRET assays.
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A potent, selective, CNS penetrant, orally bioavailable RORγt with pIC50 of 8.3 in FRET assays; has TH17 pEC50 of 7.3, demonstrates excellent in vivo efficacy in EAE mice.
| M.Wt | 518.328 | |
| Formula | C22H16Cl2F3NO4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Wang Y, et al. ACS Med Chem Lett. 2015 May 26;6(7):787-92.
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