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RS-1

Chemical Structure : RS-1

CAS No.: 312756-74-4

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RS-1 (RAD51 activator RS1)

Catalog No.: PC-45715Not For Human Use, Lab Use Only.

RS-1 is a homology-directed repair (HDR) enhancer and RAD51 activator, enhances HDR 3- to 6-fold depending on the locus and transfection method.

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5 mg $48 In stock
10 mg $68 In stock
25 mg $118 In stock
50 mg $188 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

RS-1 is a homology-directed repair (HDR) enhancer and RAD51 activator, enhances HDR 3- to 6-fold depending on the locus and transfection method.
RS-1 shows effectivity on improving knock-in rates in both the TALEN- and the CRISPR/Cas9-mediated genome-editing systems.

Physicochemical Properties

M.Wt 524.2256
Formula C20H16Br2N2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzamide, 4-bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]-

References

1. Song J, et al. Nat Commun. 2016 Jan 28;7:10548.

2. Pinder J, et al.Nucleic Acids Res. 2015 Oct 30;43(19):9379-92.

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