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Chemical Structure : RX-105
Catalog No.: PC-20581Not For Human Use, Lab Use Only.
RX-105 (RX105) is a small molecule inhibitor of protein interaction with glycosaminoglycans (SMIGs) with anti-inflammatory properties, binds directly to glycosaminoglycans (GAGs).
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RX-105 (RX105) is a small molecule inhibitor of protein interaction with glycosaminoglycans (SMIGs) with anti-inflammatory properties, binds directly to glycosaminoglycans (GAGs).
RX-105 inhibited binding of L-selectin to heparin with IC50 of 15 uM, inhibited selectin, chemokine and cytokine binding to GAGs.
RX-105 (5-50 mg/kg) inhibited paw edema dose dependently in paw edema animal model.
| M.Wt | 582.80 | |
| Formula | C29H34N4O3S3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nicholas Harris, et al. Biochim Biophys Acta. 2014 Jan;1840(1):245-54.
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