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Chemical Structure : RX-3117
Catalog No.: PC-44249Not For Human Use, Lab Use Only.
RX-3117 (TV-1360, fluorocyclopentenylcytosine) is an orally available cytidine analog, nucleoside antimetabolite with potential antineoplastic activity.
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RX-3117 (TV-1360, fluorocyclopentenylcytosine) is an orally available cytidine analog, nucleoside antimetabolite with potential antineoplastic activity; Fluorocyclopentenylcytosine (RX-3117) is activated by uridine-cytidine kinase 2 (UCK2); shows potent efficacy in xenograft models, even in tumors that are resistant to gemcitabine.
Chemotherapeutic Agents
Phase 2 Clinical
| M.Wt | ||
| Formula | C10H12FN3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 50 mg/mL |
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1. Peters GJ, et al. Invest New Drugs. 2013 Dec;31(6):1444-57.
2. Yang MY, et al. Anticancer Res. 2014 Dec;34(12):6951-9.
3. Sarkisjan D, et al. PLoS One. 2016 Sep 9;11(9):e0162901.
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