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Chemical Structure : Raltegravir potassium salt
CAS No.: 871038-72-1
Catalog No.: PC-42549Not For Human Use, Lab Use Only.
A potent, selective, orally bioavailable HIV-integrase inhibitor with IC50 of 15 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $96 | In stock | |
| 50 mg | $312 | In stock | |
| 100 mg | $480 | In stock |
Bulk size, bulk discount!
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A potent, selective, orally bioavailable HIV-integrase inhibitor with IC50 of 15 nM; essentially inactive (IC50s>50 uM) against HCV Pol, HIV RT, HIV RNase-H, and human α/β/γ Pol; shows inhibitory activity against the wild type virus and a selection of mutants; the first HIV-integrase inhibitor for the treatment of HIV-1 infection.
HIV Infection
Approved
| M.Wt | 482.5067 | |
| Formula | C20H20FKN6O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-Pyrimidinecarboxamide, N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-, potassium salt(1:1) |
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1. Summa V, et al. J Med Chem. 2008 Sep 25;51(18):5843-55.
2. Malet I, et al. Antimicrob Agents Chemother. 2008 Apr;52(4):1351-8.
3. Cooper DA, et al. N Engl J Med. 2008 Jul 24;359(4):355-65.
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