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Chemical Structure : Raltitrexed
CAS No.: 112887-68-0
Catalog No.: PC-42711Not For Human Use, Lab Use Only.
A quinazoline antifolate thymidylate synthase (TS) inhibitor with Ki of 62 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $184 | In stock | |
| 100 mg | $316 | In stock | |
| 500 mg | $885 | In stock | |
| 1 g | Get quote |
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A quinazoline antifolate thymidylate synthase (TS) inhibitor with Ki of 62 nM; inhibits TS with IC50 of 2.5 nM and L1210 tumor cell growth with IC50 of 8 nM; acitve in vivo.
Chemotherapeutic Agents
Approved
| M.Wt | 458.4876 | |
| Formula | C21H22N4O6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 29 mg/mL |
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| Chemical Name/SMILES |
L-Glutamic acid, N-[[5-[[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]- |
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1. Jackman AL, et al. Cancer Res. 1991 Oct 15;51(20):5579-86.
2. Yin MB, et al. Cancer Res. 1992 Nov 1;52(21):5900-5.
3. Pressacco J, et al. Cancer Res. 1995 Apr 1;55(7):1505-8.
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