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Chemical Structure : Refametinib R enantiomer
Catalog No.: PC-42462Not For Human Use, Lab Use Only.
The R enantiomer of Refametinib, a potent, non–ATP-competitive, highly selective, allosteric inhibitor of MEK1/2 with IC50 of 19/47 nM respectively..
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The R enantiomer of Refametinib, a potent, non–ATP-competitive, highly selective, allosteric inhibitor of MEK1/2 with IC50 of 19/47 nM respectively.
| M.Wt | 572.3372 | |
| Formula | C19H20F3IN2O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO |
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1. Iverson C, et al. Cancer Res. 2009 Sep 1;69(17):6839-47.
2. Chang Q, et al. BMC Cancer. 2010 Sep 28;10:515.
3. Schmieder R, et al. Neoplasia. 2013 Oct;15(10):1161-71.
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