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Chemical Structure : Retaspimycin hydrochloride
Catalog No.: PC-42456Not For Human Use, Lab Use Only.
A water-soluble derivative of 17-AAG and HSP90 inhibitor.
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Retaspimycin hydrochloride (IPI-504) is a water-soluble derivative of 17-AAG and HSP90 inhibitor.
Retaspimycin hydrochloride (IPI-504) induces KIT degradation, tumor shrinkage, and cell proliferation arrest in xenograft models of gastrointestinal stromal tumors.
| M.Wt | 624.1652 | |
| Formula | C31H46ClN3O8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 56 mg/mL |
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1. Floris G, et al. Mol Cancer Ther. 2011 Oct;10(10):1897-908.
2. Hanson BE, et al. Expert Opin Investig Drugs. 2009 Sep;18(9):1375-83.
3. Oh WK, et al. Urology. 2011 Sep;78(3):626-30.
4. Siegel D, et al. Leuk Lymphoma. 2011 Dec;52(12):2308-15.
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