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Chemical Structure : Reversine
CAS No.: 656820-32-5
Catalog No.: PC-21560Not For Human Use, Lab Use Only.
Reversine is a potent, ATP-competitive Aurora kinases inhibitor with IC50 of 400, 500 and 400 nM for Aurora A, Aurora B and Aurora C, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $158 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | $398 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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Reversine is a potent, ATP-competitive Aurora kinases inhibitor with IC50 of 400, 500 and 400 nM for Aurora A, Aurora B and Aurora C, respectively.
Reversine promotes the dedifferentiation of committed cells into multipotent progenitor-type cells.
Reversine inhibited colony formation of leukemic cells from patients with acute myeloid leukemia.
| M.Wt | 393.50 | |
| Formula | C21H27N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N6-Cyclohexyl-N2-(4-morpholinophenyl)-9H-purine-2,6-diamine |
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1. D'Alise AM, et al. Mol Cancer Ther2008 May;7(5):1140-9.
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