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Riluzole

Chemical Structure : Riluzole

CAS No.: 1744-22-5

Riluzole (PK26124)

Catalog No.: PC-24489Not For Human Use, Lab Use Only.

Riluzole is an anticonvulsant agent and N-methyl-D-aspartate (NMDA) glutamate receptor blocker, also is a TPC2 activator, also inhibited Kv4.2, Kv4.2/DPP6, and Kv4.2/KChIP2c channels in a voltage-independent manner, also binds to the C-terminal domain of SARS-CoV-2 nucleocapsid protein and has antiviral activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Riluzole is an anticonvulsant agent and N-methyl-D-aspartate (NMDA) glutamate receptor blocker, also is a TPC2 activator, also inhibited Kv4.2, Kv4.2/DPP6, and Kv4.2/KChIP2c channels in a voltage-independent manner, also binds to the C-terminal domain of SARS-CoV-2 nucleocapsid protein and has antiviral activity.

Physicochemical Properties

M.Wt 234.20
Formula C8H5F3N2OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(Trifluoromethoxy)benzo[d]thiazol-2-amine

References

1. He Y, et al. Neuropharmacology. 2002 Feb;42(2):199-209.

2. Delgado-Ramírez M, et al. Eur J Pharmacol. 2025 Jan 5;986:177146.

3. Márquez-Moñino MÁ, et al. Structure. 2025 Jan 2;33(1):39-50.e6.

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