Chemical Structure : Risuteganib
CAS No.: 1307293-62-4
Catalog No.: PC-35165Not For Human Use, Lab Use Only.
Risuteganib (ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis.
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	Risuteganib (ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis.
	ALG1001 inhibits an integrin-mediated pathway of the vitreoretinal interface, connecting the posterior aspect of the vitreous with the internal limiting membrane of the retina.
	In blocking this pathway, ALG-1001 helps to achieve vitreous breakdown and separation from the retina.
| M.Wt | 637.666 | |
| Formula | C22H39N9O11S | |
| Appearance | Solid | |
| Storage | 
                            
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| Solubility | 
                             10 mM in DMSO  | 
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| Chemical Name/SMILES | 
                             L-Proline, glycyl-L-arginylglycyl-3-sulfo-L-alanyl-L-threonyl-  | 
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	1. Yang P, et al. Invest Ophthalmol Vis Sci. 2020 Aug 3;61(10):35.
	2. Schneider K, et al. Exp Eye Res. 2021 Feb;203:108287.

                
                
                
                
                
                
                
                
            
            
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