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Ro3280

Chemical Structure : Ro3280

CAS No.: 1062243-51-9

Ro3280 (Ro 3280)

Catalog No.: PC-21169Not For Human Use, Lab Use Only.

Ro3280 is a potent, specific PLK1 inhibitor with IC50/Kd of 3/0.09 nM, respectively, shows no activity against PLK2/3.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ro3280 is a potent, specific PLK1 inhibitor with IC50/Kd of 3/0.09 nM, respectively, shows no activity against PLK2/3.

Physicochemical Properties

M.Wt 543.62
Formula C27H35F2N7O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methyl-4-piperidinyl)benzamide

References

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