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Roseoflavin

Chemical Structure : Roseoflavin

CAS No.: 51093-55-1

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Roseoflavin (8-Dimethylaminoriboflavin)

Catalog No.: PC-70093Not For Human Use, Lab Use Only.

Roseoflavin is a chemical analog of FMN and riboflavin that has antimicrobial activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Roseoflavin is a chemical analog of FMN and riboflavin that has antimicrobial activity; directly bind to FMN riboswitch aptamers (Kd=100 nM) and downregulate the expression of an FMN riboswitch-lacZ reporter gene in B. subtilis.

Physicochemical Properties

M.Wt 405.4
Formula C18H23N5O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

8-(dimethylamino)-7-methyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione

References

1. Lee ER, et al. RNA Biol. 2009 Apr-Jun;6(2):187-94.

2. Wang H, et al. Cell Chem Biol. 2017 May 18;24(5):576-588.e6.

3. Langer S, et al. J Bacteriol. 2013 Sep;195(18):4037-45.

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