Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Roxyl-WL
Catalog No.: PC-35526Not For Human Use, Lab Use Only.
Roxyl-WL is a highly potent and selective inhibitor of IDO1 with IC50 of 1 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Roxyl-WL is a highly potent and selective inhibitor of IDO1 with IC50 of 1 nM; displays excellent kinase spectrum selectivity with no activity out of the 337 protein kinases; effectively augmentes the proliferation of T cells and reduces the number of regulatory T cell (Tregs), significantly suppresses tumor growth and induces immune response in melanoma (B16F10) tumor-bearing mice orally.
| M.Wt | 370.372 | |
| Formula | C20H14N6O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Xu G, et al. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1089-1094.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
