Chemical Structure : S-thanatin
CAS No.:
1027105-06-1
S-thanatin
Catalog No.: PC-28584Not For Human Use, Lab Use Only.
S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity, inhibits the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, binds negatively charged LPS and anionic lipid, ihhibits membrane respiration, exhaustes the intracellular potential, and releases periplasmic material, leding to cell death.
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Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity, inhibits the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, binds negatively charged LPS and anionic lipid, ihhibits membrane respiration, exhaustes the intracellular potential, and releases periplasmic material, leding to cell death.
Physicochemical Properties
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M.Wt
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2421.91
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Formula
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C102H177N35O27S3
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20°C 12 Months; 4°C 6 Months
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- In Solvent
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-80°C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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Gly-Ser-Lys-Lys-Pro-Val-Pro-Ile-Ile-Tyr-Cys-Asn-Arg-Arg-Ser-Gly-Lys-Cys-Gln-Arg-Met
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References
1. Fan X, et al. Front Pharmacol. 2015 Oct 27;6:249.
2. Wu G, et al. Biochem Biophys Res Commun. 2010 Apr 23;395(1):31-5.
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