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Chemical Structure : S1P1 Agonist 8
Catalog No.: PC-43245Not For Human Use, Lab Use Only.
S1P1 Agonist 8 is a potent, selective, orally bioavailable S1P1 receptor agonist with EC50 of 35 nM (S1P1 internalization), >100-fold selectivity over against receptor subtypes S1P2-5.
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S1P1 Agonist 8 is a potent, selective, orally bioavailable S1P1 receptor agonist with EC50 of 35 nM (S1P1 internalization), >100-fold selectivity over against receptor subtypes S1P2-5; induces dose-dependent reduction in lymphocyte count in rats.
| M.Wt | 415.3652 | |
| Formula | C21H16F3N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Harrington PE, et al. ACS Med Chem Lett. 2011 Nov 23;3(1):74-8.
2. Pennington LD, et al. ACS Med Chem Lett. 2011 Jul 29;2(10):752-7.
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