S22153 | Melatonin receptor antagonist

Chemical Structure : S22153

CAS No.: 180304-07-8

Catalog No.: PC-26547Not For Human Use, Lab Use Only.

S-22153 is a potent melatonin receptor antagonist with EC50 of 19 nM, 4.6 nM for hMT1 and hMT2 melatonin receptor, respectively.

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Biological Activity

S-22153 is a potent melatonin receptor antagonist with EC50 of 19 nM, 4.6 nM for hMT1 and hMT2 melatonin receptor, respectively.

M.Wt	247.36
Formula	C14H17NOS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(5-ethylbenzo[b]thiophen-3-yl)ethyl)acetamide

1. Weibel L, et al. Brain Res. 1999 May 22;829(1-2):160-6.

2. Kopp C, et al. Pharmacol Biochem Behav. 1999 Sep;64(1):131-6.

3. Audinot V, et al. Naunyn Schmiedebergs Arch Pharmacol. 2003 Jun;367(6):553-61.