Catalog No.: PC-21016Not For Human Use, Lab Use Only.
SARS-CoV-2 3CLpro inhibitor C5a is a potent, non-covalent, non-peptide inhibitor of 3C-like protease (3CLpro) inhibitor with dissociation constant (Kd) of 170 nM, IC50 of 0.7 uM against recombinant SARS-CoV-2 3CLpro.
SARS-CoV-2 3CLpro inhibitor C5a is a potent, non-covalent, non-peptide inhibitor of 3C-like protease (3CLpro) inhibitor with dissociation constant (Kd) of 170 nM, IC50 of 0.7 uM against recombinant SARS-CoV-2 3CLpro.
SARS-CoV-2 3CLpro inhibitor C5a exhibits broad-spectrum activity against Omicron subvariants (BA.5, BQ.1.1, and XBB.1.5) and seasonal human coronavirus-229E infection in human cells.
SARS-CoV-2 3CLpro inhibitor C5a shows has MEC50 of 30-50 nM against BQ.1.1 and XBB.1.5 in two different human cell lines.
SARS-CoV-2 3CLpro inhibitor C5a exhibits synergistic action in combination with N-0385 and BafD against Omicron BA.5 infection in human Calu-3 lung cells.
