Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : SARS-CoV-2 3CLpro inhibitor C5a
Catalog No.: PC-21016Not For Human Use, Lab Use Only.
SARS-CoV-2 3CLpro inhibitor C5a is a potent, non-covalent, non-peptide inhibitor of 3C-like protease (3CLpro) inhibitor with dissociation constant (Kd) of 170 nM, IC50 of 0.7 uM against recombinant SARS-CoV-2 3CLpro.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
SARS-CoV-2 3CLpro inhibitor C5a is a potent, non-covalent, non-peptide inhibitor of 3C-like protease (3CLpro) inhibitor with dissociation constant (Kd) of 170 nM, IC50 of 0.7 uM against recombinant SARS-CoV-2 3CLpro.
SARS-CoV-2 3CLpro inhibitor C5a exhibits broad-spectrum activity against Omicron subvariants (BA.5, BQ.1.1, and XBB.1.5) and seasonal human coronavirus-229E infection in human cells.
SARS-CoV-2 3CLpro inhibitor C5a shows has MEC50 of 30-50 nM against BQ.1.1 and XBB.1.5 in two different human cell lines.
SARS-CoV-2 3CLpro inhibitor C5a exhibits synergistic action in combination with N-0385 and BafD against Omicron BA.5 infection in human Calu-3 lung cells.
| M.Wt | 451.97 | |
| Formula | C24H22ClN3O2S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Jimena Pérez-Vargas, et al. Emerg Microbes Infect. 2023 Aug 9;2246594.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
