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Chemical Structure : SB-590885
CAS No.: 405554-55-4
Catalog No.: PC-42755Not For Human Use, Lab Use Only.
SB-590885 is a potent and selective B-Raf inhibitor with Kd of 0.3 nM, >1000 fold selectivity over p38a, GSK3b and Lck.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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SB-590885 is a potent and selective B-Raf inhibitor with Kd of 0.3 nM, >1000 fold selectivity over p38a, GSK3b and Lck.
| M.Wt | 453.5356 | |
| Formula | C27H27N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1H-Inden-1-one, 5-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1H-imidazol-4-yl]-2,3-dihydro-, oxime |
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1. Takle AK, et al. Bioorg Med Chem Lett. 2006 Jan 15;16(2):378-81.
2. King AJ, et al. Cancer Res. 2006 Dec 1;66(23):11100-5.
3. Villanueva J, et al. Cancer Cell. 2010 Dec 14;18(6):683-95.
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