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Chemical Structure : SB 203580 hydrochloride
CAS No.: 869185-85-3
Catalog No.: PC-42492Not For Human Use, Lab Use Only.
A specific p38 MAPK inhibitor with IC50 of 0.6 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $64 | In stock | |
| 100 mg | $96 | In stock | |
| 200 mg | $168 | In stock |
Bulk size, bulk discount!
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A specific p38 MAPK inhibitor with IC50 of 0.6 uM; shows selectivity over JNK, p42 MAPK, p90 S6K, p70 S6K, PKA, etc.; suppresses the activation of MAPKAP kinase-2 and prevents the phosphorylation of HSP27 in response to interleukin-1, cellular stresses and bacterial endotoxin in vivo.
| M.Wt | 413.8956 | |
| Formula | C21H17ClFN3OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: 8.43 mg/mL |
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| Chemical Name/SMILES |
Pyridine, 4-[4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]-, hydrochloride (1:1) |
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1. Cuenda A, et al. FEBS Lett. 1995 May 8;364(2):229-33.
2. Lali FV, et al. J Biol Chem. 2000 Mar 10;275(10):7395-402.
3. Badger AM, et al. J Pharmacol Exp Ther. 1996 Dec;279(3):1453-61.
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