SBFI-1143

Chemical Structure : SBFI-1143

Catalog No.: PC-26227Not For Human Use, Lab Use Only.

SBFI-1143 is a specific small molecule fatty acid binding protein 5 (FABP5) inhibitor with Ki of 0.65 uM, with limited activity against FABP3/FABP7.

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Biological Activity

SBFI-1143 is a specific small molecule fatty acid binding protein 5 (FABP5) inhibitor with Ki of 0.65 uM, with limited activity against FABP3/FABP7.

M.Wt	628.68
Formula	C39H32O8
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1S,2S,3S,4S)-3-(((4-(benzo[d][1,3]dioxol-5-yl)-[1,1'-biphenyl]-2-yl)oxy)carbonyl)-2,4-bis(2-methoxyphenyl)cyclobutane-1-carboxylic acid

1. Shubhra Rajput, et al. Cancers (Basel). 2025 Nov 21;17(23):3723.

2. Yan S, et al. Eur J Med Chem. 2018;154:233–252.

3. Hehe Wang, et al. Bioorg Med Chem. 2025 May 1:122:118136.