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SC-806

Chemical Structure : SC-806

CAS No.: 216505-89-4

SC-806 (SC 806;SC806)

Catalog No.: PC-61210Not For Human Use, Lab Use Only.

A potent, orally active p38 MAPK inhibitor with IC50 of 50 nM, significantly decreases incidence of arthritis in mouse collagen-induced arthritis..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent, orally active p38 MAPK inhibitor with IC50 of 50 nM, significantly decreases incidence of arthritis in mouse collagen-induced arthritis.

Physicochemical Properties

M.Wt 353.854
Formula C19H20ClN5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(5-(4-chlorophenyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl)-4-methylpiperazine

References

1. Graneto MJ, et al. J Med Chem. 2007 Nov 15;50(23):5712-9.

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