SC023 | SERCA2a SUMOylation activator | Probechem Biochemicals

Chemical Structure : SC023

SC023 (SC-023)

Catalog No.: PC-27370Not For Human Use, Lab Use Only.

Packing	Price	Stock	Quantity

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

SC023 is a second-generation N106 analog and small-molecule enhancer of SERCA2a SUMOylation, targets the SUMO E1 enzyme to trigger intrinsic SERCA2a SUMOylation without altering SUMO-related regulatory enzymes.
SC023 exhibits reduced off-target activity, specifically lacking the adenosine A2A and serotonin 5-HT2B receptor inhibition observed with N106.
SC023 overcomes the PK and safety limitations of N106.
SC023 significantly restored left ventricular systolic function and attenuated adverse remodeling in murine transverse aortic constriction model.

Physicochemical Properties

M.Wt
Formula
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

References

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

SC023 (SC-023)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.