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Chemical Structure : SCF-I2
CAS No.: 99827-46-0
Catalog No.: PC-61192Not For Human Use, Lab Use Only.
SCF-I2 is an allosteric, sepecific inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase with IC50 of 6.2 uM in FP assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $188 | In stock | |
| 10 mg | $288 | In stock | |
| 25 mg | $478 | In stock | |
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| 100 mg | Get quote |
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SCF-I2 is an allosteric, sepecific inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase with IC50 of 6.2 uM in FP assays.
SCF-I2 does not affect the activity of the closely related E3 enzyme SCFMet30.
SCF-I2 inhibits binding and/or ubiquitination of both full length Sic1 and Far1 with IC50 of 60 uM.
| M.Wt | 342.35 | |
| Formula | 22H14O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1-(2-carboxynaphth-1yl)-2-naphthoic acid |
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1. Orlicky S, et al. Nat Biotechnol. 2010 Jul;28(7):733-7.
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