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Chemical Structure : SCH 221510
Catalog No.: PC-60797Not For Human Use, Lab Use Only.
A potent, selective, orally active nociceptin opioid receptor (NOP) agonist with EC50 of 12 nM, Ki of 0.3 nM.
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A potent, selective, orally active nociceptin opioid receptor (NOP) agonist with EC50 of 12 nM, Ki of 0.3 nM; displays >50-fold over the mu-, kappa-, and delta-opioid receptors; produces anxiolytic-like effects in rats, does not disrupt overt behavior.
| M.Wt | 397.562 | |
| Formula | C28H31NO | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Varty GB, et al. J Pharmacol Exp Ther. 2008 Aug;326(2):672-82.
2. Sobczak M, et al. J Pharmacol Exp Ther. 2014 Mar;348(3):401-9.
3. Cremeans CM, et al. J Pharmacol Exp Ther. 2012 Oct;343(1):72-81.
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