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Chemical Structure : SCH 58261
CAS No.: 160098-96-4
Catalog No.: PC-45642Not For Human Use, Lab Use Only.
SCH 58261 is a potent and selective, competitive A2A adenosine receptor antagonist with Ki of 2.3 nM and 2.0 nM in rat and bovine brain, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $348 | In stock | |
| 100 mg | Get quote |
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SCH 58261 is a potent and selective, competitive A2A adenosine receptor antagonist with Ki of 2.3 nM and 2.0 nM in rat and bovine brain, respectively.
SCH 58261 displays 323-, 53- and 100-fold selectivity over A1, A2B and A3 receptors, respectively.
SCH 58261 reverses reperfusion injury (IR) increased hippocampal Glu, GABA, glycine and aspartate, MPO, TNF-α, nitric oxide, and PGE in Male Wistar rats.
| M.Wt | 345.358 | |
| Formula | C18H15N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 34 mg/mL |
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| Chemical Name/SMILES |
7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)- |
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1. Zocchi C, et al. J Pharmacol Exp Ther. 1996 Feb;276(2):398-404.
2. Beavis PA, et al. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14711-6.
3. Mohamed RA, et al. Neurochem Res. 2012 Mar;37(3):538-47.
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