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Chemical Structure : SCH 79797 dihydrochloride
CAS No.: 1216720-69-2
Catalog No.: PC-61305Not For Human Use, Lab Use Only.
SCH79797 dihydrochloride is a potent, selective competitive and nonpeptide PAR-1 antagonist with IC50 of 70 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $338 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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SCH79797 dihydrochloride is a potent, selective competitive and nonpeptide PAR-1 antagonist with IC50 of 70 nM.
SCH79797 inhibits α-thrombin- and haTRAP-induced aggregation of human platelets, but does inhibits human platelet aggregation induced by the tethered ligand agonist for PAR-4, γ-thrombin, ADP, or collagen.
SCH79797 also blocks angiogenesis association with endothelial cell growth suppression and induction of apoptosis.
| M.Wt | 444.41 | |
| Formula | C23H25N5.2HCl | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N3-Cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine dihydrochloride |
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1. Ahn HS, et al. Biochem Pharmacol. 2000 Nov 15;60(10):1425-34.
2. Ahn HS, et al. Bioorg Med Chem Lett. 1999 Jul 19;9(14):2073-8.
3. Zania P, et al. J Pharmacol Exp Ther. 2006 Jul;318(1):246-54.
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