SCM-18

Chemical Structure : SCM-18

Catalog No.: PC-24396Not For Human Use, Lab Use Only.

SCM-18 is a potent, highly selective, non-suicide CYP3A4 inhibitor with IC50 of 0.36 uM, has >170 fold selectivity over CYP3A5 (IC50>60 uM).

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Biological Activity

SCM-18 is a potent, highly selective, non-suicide CYP3A4 inhibitor with IC50 of 0.36 uM, has >170 fold selectivity over CYP3A5 (IC50>60 uM).

M.Wt	380.76
Formula	C17H12ClF3N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(2-chlorophenyl)urea

1. Jingheng Wang, et al. Nat Commun. 2025 Apr 10;16(1):3423.