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SCoV2 Plpro-Probe-7

Chemical Structure : SCoV2 Plpro-Probe-7

CAS No.: 2644015-19-8

SCoV2 Plpro-Probe-7

Catalog No.: PC-72491Not For Human Use, Lab Use Only.

SCoV2 Plpro-Probe-7 is a peptidomimetic activity probe and substrate for SCoV2 PLpro, exhibits excellent sensitivity to wild-type (WT) SCoV2 PLpro, but not to the catalytically inactive mutant, SCoV2 PLproC112S, consists of a fluorogenic HCC conjugated to PLpro's N terminus, and DABCYL to its C-terminal lysine.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SCoV2 Plpro-Probe-7 is a peptidomimetic activity probe and substrate for SCoV2 PLpro, exhibits excellent sensitivity to wild-type (WT) SCoV2 PLpro, but not to the catalytically inactive mutant, SCoV2 PLproC112S, consists of a fluorogenic HCC conjugated to PLpro's N terminus (RLRGG), and DABCYL to its C-terminal lysine.

Physicochemical Properties

M.Wt 1067.223
Formula C51H70N16O10
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Hengyue Shan, et al. Cell Chem Biol. 2021 Jun 17;28(6):855-865.e9.

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