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Chemical Structure : SI-109
CAS No.: 2429877-30-3
Catalog No.: PC-73110Not For Human Use, Lab Use Only.
SI-109 (SI 109) is a selective, high-affinity and cell-permeable STAT3 SH2 domain inhibitor with Ki of 9 nM, component of STAT3 degrader SD-36 (PROTAC).
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SI-109 (SI 109) is a selective, high-affinity and cell-permeable STAT3 SH2 domain inhibitor with Ki of 9 nM, component of STAT3 degrader SD-36 (PROTAC).
| M.Wt | 808.82 | |
| Formula | C40H47F2N6O8P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
((2-(((3S,6S,10aS)-3-(((S)-5-amino-1-(benzhydrylamino)-1,5-dioxopentan-2-yl)carbamoyl)-5-oxodecahydropyrrolo[1,2-a]azocin-6-yl)carbamoyl)-1H-indol-5-yl)difluoromethyl)phosphonic acid |
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1. Bai L, et al. Cancer Cell. 2019 Nov 11;36(5):498-511.e17.
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