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SK-7041

Chemical Structure : SK-7041

CAS No.: 617690-98-9

SK-7041 (SK7041;SK 7041)

Catalog No.: PC-70233Not For Human Use, Lab Use Only.

SK-7041 is a potent HDAC inhibitor with IC50 of 172 nM, preferentially inhibit class I HDAC1 and HDAC2 than the other HDAC isotypes.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SK-7041 is a potent HDAC inhibitor with IC50 of 172 nM, preferentially inhibit class I HDAC1 and HDAC2 than the other HDAC isotypes.
    SK-7041 exhibits potent antiproliferative activity against various human cancer cells in vitro, and reduces the growth of implanted human tumors in nude mice.

    Physicochemical Properties

    M.Wt 339.395
    Formula C19H21N3O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-4-(dimethylamino)-N-(4-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzyl)benzamide

    References

    1. Ryu JK, et al. Cancer Lett. 2006 Jun 8;237(1):143-54.

    2. Park JH, et al. Clin Cancer Res. 2004 Aug 1;10(15):5271-81.

    3. Lee KW, et al. Anticancer Res. 2006 Sep-Oct;26(5A):3429-38.

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