Chemical Structure : SLOS-1811-06 tR1
Catalog No.: PC-26889Not For Human Use, Lab Use Only.
SLOS-1811-06 tR1 is a potent, small molecule activator of NRF2 with EC50 of 0.98 nM in ARE-luciferase reporter assays, shows inhibitory activity of NRF2-KEAP1 with IC50 of 0.17 nM in BRET assays, protects hiPSC-derived RGCs from hypoxia/reoxygenation injury.
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SLOS-1811-06 tR1 is a potent, small molecule activator of NRF2 with EC50 of 0.98 nM in ARE-luciferase reporter assays, shows inhibitory activity of NRF2-KEAP1 with IC50 of 0.17 nM in BRET assays, protects hiPSC-derived RGCs from hypoxia/reoxygenation injury.
| M.Wt | 542.67 | |
| Formula | C27H30N2O6S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Miyabe T, et al. Exp Eye Res. 2026 May 19:111078.

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