SLU-1642 | P. aeruginosa MexF inhibitor

Chemical Structure : SLU-1642

SLU-1642 (SLU1642)

Catalog No.: PC-28760Not For Human Use, Lab Use Only.

SLU-1642 is a specific small-molecule inhibitor that selectively targets P. aeruginosa MexF and its closest homologs, but not major efflux pumps such as MexB, specifically potentiates the activity of antibiotic substrates of MexF in P. aeruginosa hyperporinated strains overexpressing MexF.

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Biological Activity

SLU-1642 is a specific small-molecule inhibitor that selectively targets P. aeruginosa MexF and its closest homologs, but not major efflux pumps such as MexB, specifically potentiates the activity of antibiotic substrates of MexF in P. aeruginosa hyperporinated strains overexpressing MexF.

Physicochemical Properties

M.Wt	360.90
Formula	C18H21ClN4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-(1H-imidazol-1-yl)propyl)-6-chloro-N-(cyclopropylmethyl)-4-methylbenzo[d]thiazol-2-amine

References

1. Uddin MR, et al. Antimicrob Agents Chemother. 2026 Nov 2:e0070626.

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SLU-1642 (SLU1642)

Biological Activity

Physicochemical Properties

References

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