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Chemical Structure : SMER-18
CAS No.: 944153-47-3
Catalog No.: PC-45515Not For Human Use, Lab Use Only.
SMER-18 is a small molecule autophagy enhancer that induces autophagy independently of rapamycin in mammalian cells and enhances the clearance of autophagy substrates such as mutant huntingtin and A53T alpha-synuclein.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $358 | In stock | |
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| 50 mg | Get quote | ||
| 100 mg | Get quote |
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SMER-18 is a small molecule autophagy enhancer that induces autophagy independently of rapamycin in mammalian cells and enhances the clearance of autophagy substrates such as mutant huntingtin and A53T alpha-synuclein.
SMER-18 reduces toxicity in Huntington's disease models.
| M.Wt | 287.7409 | |
| Formula | C16H14ClNO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-Buten-1-one, 1-(4-chlorophenyl)-3-[(3-hydroxyphenyl)amino]-, (2Z)- |
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1. Sarkar S, et al. Nat Chem Biol. 2007 Jun;3(6):331-8.
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