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SN38023

Chemical Structure : SN38023

CAS No.: 2380002-71-9

SN38023 (SN 38023)

Catalog No.: PC-20221Not For Human Use, Lab Use Only.

SN38023 is a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361 (Cat# PC-62995), SN38023 is metabolised to a potent DNA-PKi (IC87361) selectively in radioresistant hypoxic cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SN38023 is a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361 (Cat# PC-62995), SN38023 is metabolised to a potent DNA-PKi (IC87361) selectively in radioresistant hypoxic cells.

Physicochemical Properties

M.Wt 462.46
Formula C24H22N4O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-[(1-Methyl-2-nitro-1H-imidazol-5-yl)methoxy]-7-(4-morpholinyl)-2-phenyl-4H-1-benzopyran-4-one

References

1. Way Wua Wong, et al. Biochem Pharmacol. 2019 Nov;169:113641.

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