Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : SOR-C13 TFA
CAS No.: 1187852-48-7 (free acid)
Catalog No.: PC-22127Not For Human Use, Lab Use Only.
SOR-C13 TFA, a carboxy-terminal truncated peptide, is a high-affinity, selective TRPV6 calcium channel inhibitor with IC50 of 14 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $258 | In stock | |
| 25 mg | $428 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
SOR-C13 TFA, a carboxy-terminal truncated peptide, is a high-affinity, selective TRPV6 calcium channel inhibitor with IC50 of 14 nM.
SOR-C13 binds to TRPV6 in ovarian cancer cells with high affinity.
SOR-C13 inhibit calcium influx in TRPV6 over-expressing cells and is more effective at reducing cell viability than cis-Platin.
SOR-C13 (400, 600 and 800 mg/kg, daily i.p.) over 12 days significantly reduces ovarian tumour growth in NOD/SCID mice bearing xenografted ovarian tumours.
| M.Wt | 1565.81 (free acid) | |
| Formula | C72H116N20O19.xC2HF3O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Lys-Glu-Phe-Leu-His-Pro-Ser-Lys-Val-Asp-Leu-Pro-Arg |
|
1. Bowen CV, et al. PLoS One. 2013;8(3):e58866.
2. Xue H, et al. J Cancer. 2018 Aug 6;9(17):3196-3207.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
