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SPI009

Chemical Structure : SPI009

CAS No.: 1008671-41-7

SPI009 (SPI 009)

Catalog No.: PC-61788Not For Human Use, Lab Use Only.

SPI009 is a novel antipersister compound active against P. aeruginosa.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SPI009 is a novel antipersister compound active against P. aeruginosa; reduces the number of persisters up to 100,000-fold in both lab strains and clinical isolates of P. aeruginosa when combined with distinct classes of antibiotics; efficiently kills persister cells with minor cytotoxicity, and causes no erythrocyte damage.

Physicochemical Properties

M.Wt 340.244
Formula C17H19Cl2NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-[(2,4-dichlorophenethyl)amino]-3-phenoxypropan-2-ol

References

1. Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00836-17.

2. Defraine V, et al. Front Microbiol. 2017 Dec 22;8:2585.

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